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On April 16:
1912 — Christian Ruckmick described the status of early experimental psychology in a presentation to the Society of Experimental Psychologists. He reported that the average annual salary of a full professor was $2,500 and that the wealthiest psychology department was that of Columbia University, with a total salary and operating budget of $13,549.
1913 — The Henry Phipps Psychiatric Clinic, one of the divisions of the Johns Hopkins Hospital, was opened. Adolph Meyer was the first director of the clinic.
1943 — Albert Hofmann, a research chemist at the Sandoz Laboratories (now Novartis Pharmaceuticals) in Basel, Switzerland, left work due to "a remarkable restlessness" and "dizziness." Later, he experienced a "stream of fantastic pictures, extraordinary shapes" and "intense...colors." Dermal absorption of LSD-25, a substance he was working with, was the suspected cause. Although unintentional, this was the first LSD-induced psychedelic experience.
1959 — The antidepressant drug Tofranil (imipramine; Rorer and Geigy) was approved for use by the U.S. Food and Drug Administration (FDA). Imipramine was the first tricyclic antidepressant. It probably enhances neurotransmission by blocking reuptake of the neurotransmitter norepinephrine. Janimine (Abbott Laboratories) is also imipramine and was approved by the FDA on April 8, 1977.